The AxiaLIF+® (Axial Lumbar Interbody Fusion) System is designed to create a safe and reproducible anterior retroperitoneal pre-sacral access route to the L5-S1 vertebral bodies.

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AxiaLIF+ must be used with supplemental fixation. Please see indications for use.

The AxiaLIF+® (Axial Lumbar Interbody Fusion) System is designed to create a safe and reproducible anterior retroperitoneal pre-sacral access route to the L5-S1 vertebral bodies.

The featured instrumentation is designed to enable standard of care fusion principles, distraction, and stabilization of the anterior lumbar column, while mitigating the soft tissue trauma associated with traditional lumbar fusion.

Every step of the AxiaLIF+® procedure – Access, Discectomy, Grafting, Distraction, and Stabilization – is designed to produce quality patient outcomes including excellent fusion rates and low complication rates with procedural efficiencies in mind.

AxiaLIF+ spinal implant

TranS1’s foundational solution, AxiaLIF+, requires only a 2 cm incision size, which reduces blood loss, inpatient stay, and interoperative time – all while achieving a 94% fusion rate.*

With AxiaLIF, the fact that you don’t violate any of the muscular or ligamentus structures of the spine to get to your target is a huge benefit. That’s what appeals to me — you have the natural access corridor to get to the disc without damaging the patient’s anatomy.

Dr. David Hart, MD

Neurosurgeon, Wake Forest Baptist Health

Biomechanical Stability

Numerous studies have documented the excellent fusion rate and biomechanical stability of AxiaLIF+®.  (1,2,3,4) The strength of the implant enables surgeons to build a strong foundation at the base of the spine.

Individualized Approach

The internal distraction rod in AxiaLIF+® allows surgeons to individualize distraction in situ based on each patient’s needs.  This highly adjustable distraction is achieved as the internal rod is advanced between robust, static anchors.

Shaped for Success

The bone-engagement surfaces on the superior aspect of the implants have a full taper design in which each revolution cuts new, larger threads in the endplate.

Minimal Trauma

The patented pre-sacral approach AxiaLIF+® causes less patient blood loss, less operating room time, and quick patient recovery.(1,2,3,4)

The AxiaLIF+® implant first received FDA 510(k) clearance in 2006.


Arthrodesis, pre-sacral approach designated as a Category 1, non-experimental CPT Code (22586)

14,000+ procedures performed

Over 85 published research studies support the efficacy, safety and long-term outcomes of AxiaLIF+.

1. Bradley WD, Hisey MS, Verma-Kurvari S, Ohnmeiss DD. Minimally invasive trans-sacral approach to L5-S1 interbody fusion: Preliminary results from 1 center and review of the literature. Int J Spine Surg. 2012;6:110-4. PubMed PMID: 25694879; PubMed Central PMCID: PMC4300883.

2. Marchi L, Oliveira L, Coutinho E, Pimenta L. Results and complications after 2-level axial lumbar interbody fusion with a minimum 2-year follow-up. J Neurosurg Spine. 2012 Sep;17(3):187-92. PubMed PMID: 22803626.

3. Tobler WD, Gerszten PC, Bradley WD, Raley TJ, Nasca RJ, et al. Minimally invasive axial presacral L5-S1 interbody fusion: two-year clinical and radiographic outcomes. Spine (Phila Pa 1976). 2011 Sep 15;36(20):E1296-301. PubMed PMID: 21494201.

4. Aryan HE, Newman CB, Gold JJ, Acosta FL Jr, Coover C, Ames CP..2008. Percutaneous axial lumbar interbody fusion (AxiaLIF) of the L5-S1 segment: initial clinical and radiographic experience. Minim Invasive Neurosurg. 51(4):225-30. Pubmed PMID: 18683115

5. Mistry AM, Godil SS, Parker SL, McGirt MJ. Axial presacral lumbar interbody fusion: a systematic literature review. J Manag Care Med. 2014;17(3):47-56.

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