Building Better Pathways™

TranS1 is a medical device company focused on delivering elegant solutions to surgeons that minimize the damage caused by traditional surgical approaches to the spine.

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TranS1 offers a full suite of MIS spine products to complement its foundational solutions:

The AxiaLIF®+ System for pre-sacral interbody fusion, The KeyLIF System for Kambin’s triangle interbody fusion, and Pylon MIS Posterolateral Graft Delivery System.

3D animation intended to show pathway and anatomic location of TranS1 devices.  Animation does not represent clinical intended use.  Please see indication for use for each respective device.

The AxiaLIF+® (Axial Lumbar Interbody Fusion) System is designed to create a safe and reproducible anterior retroperitoneal pre-sacral access route to the L5-S1 vertebral bodies.
The TranS1 KeyLIF Oblique Lateral Lumbar Interbody Fusion System features over-the-wire insertion to support cage placement through Kambin’s Triangle.
The Pylon MIS Posterolateral Graft Delivery System allows for dilation, bony preparation, and graft placement in a controlled and minimally invasive manner.  Uses for this system include fusion site preparation along the lumbar transverse processes.
“TranS1’s unique R&D capabilities provides surgeons like myself with the tools to develop concepts into medical breakthroughs.” James Manzanares, MD

Orthopedic Surgeon

“With AxiaLIF+, the fact that you don’t violate any of the muscular or ligamentus structures of the spine to get to your target is a huge benefit. That’s what appeals to me — you have the natural access corridor to get to the disc without damaging the patient’s anatomy.” David Hart, MD


“The paracoccygeal transsacral approach gives advantages access to the spine from an anterior approach while the patient remains positioned prone for the entire surgery.  This permits the posterior decompression/fixation to be performed without adding time or repositioning or redraping the patient.” Richard Nasca, MD and William Tobler, MD

Benzel's Spine Surgery, 6th Edition, 2016, p. 756.

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